MOTS C Peptide 30mg (R&D Only)

MOTS C Peptide 30mg (R&D Only)

MOTS-C Peptide is a research grade, lyophilized mitochondrial derived peptide (MDP) encoded directly within the mitochondrial genome. Consisting of 16 amino acids, MOTS-C is one of the most scientifically significant mitochondrial derived peptides identified to date. Unlike conventional peptides that originate from nuclear DNA, MOTS-C is produced within the mitochondria, the organelles responsible for generating cellular energy, giving it a uniquely direct influence on metabolic and bioenergetic processes.

This 30mg vial of MOTS-C Peptide is formulated to the highest purity standards, intended exclusively for in vitro and preclinical research applications by qualified investigators and licensed research institutions.

How MOTS-C Works at the Cellular Level

MOTS-C Peptide operates through a sophisticated mechanism that begins in the mitochondria and extends to the cell nucleus. Research has shown that MOTS-C activates the AMPK pathway, a master regulator of cellular energy balance. By doing so, it orchestrates a genome-wide metabolic response that closely mirrors the effects produced by physical exercise, a process researchers describe as mitohormesis.

Specifically, MOTS C Peptide promotes glucose uptake in skeletal muscle cells, improves insulin stimulated glucose transport, and reduces the accumulation of toxic lipid metabolites. Studies have also demonstrated that circulating MOTS-C levels rise naturally in response to physical exercise, establishing it as a genuine exercise induced mitokine with broad physiological relevance.

Key Areas of Research Interest

Preclinical studies have investigated MOTS-C Peptide across several major research domains. In the field of metabolic disease research, MOTS-C has shown the ability to improve insulin sensitivity and reduce markers of insulin resistance in high fat diet animal models. In obesity and glucose homeostasis research, elevated plasma MOTS-C levels have been inversely correlated with obesity onset, suggesting a regulatory role in adipogenesis and energy expenditure.

In longevity and aging research, MOTS-C plasma concentrations have been found to decline with age, and exogenous administration has demonstrated the ability to restore physical performance in aged animal subjects. Elderly mice treated with MOTS-C in one landmark study were able to outperform untreated middle aged controls on multiple physical endurance measures. Additional research has explored MOTS-C’s potential relevance to cardiovascular health, inflammation reduction, and neuroprotection.

MOTS-C Peptide Specifications

Each vial of MOTS-C Peptide 30mg contains lyophilized powder of analytical grade purity, confirmed by third party mass spectrometry and HPLC testing. The peptide sequence corresponds to the validated mitochondrial open reading frame 7C (MOTS-c) with a molecular weight of approximately 2173 Da. Recommended storage is at minus 20 degrees Celsius, protected from light and moisture, to preserve structural integrity during the research period.

Disclaimer: MOTS-C Peptide is supplied strictly for laboratory and preclinical research purposes.